A couple very good articles have recently been published that give a thorough overview of transferring and syncing files between a desktop computer and an iPad. For example, you can create a Word doc on your desktop computer, save it to Dropbox, and then open it on your iPad and edit it via an office app such as Office2 or Documents to Go. The revised version then syncs automatically back to your desktop computer via Dropbox. Macworld has a very helpful article titled How to transfer files to and from an iPad and T-GAAP has an article titled Breaking the Bond Between iTunes and the iOS. The latter covers how to sync the following file types using iTunes and/or using third-party approaches: apps, photos, books, TV shows, movies, podcasts, music, ringtones, address book, calendar, email, bookmarks, notes, and application files. Many of these options are also available for the iPhone.